PubCompare

PubCompare is a specialized search engine and repository for real experimental protocols. It aggregates 25+ million full-text protocols from peer-reviewed publications, over 16 million closed-access protocols behind paywalls, and 1 million full-text protocols from patents. The platform emphasizes AI-assisted protocol discovery, comparison, reproducibility insights, and linkage to associated literature and products, enabling researchers to design robust methodologies with reduced failures. It is designed to streamline literature reviews, protocol selection, and cross-publication benchmarking, helping researchers save time and improve transparency and reproducibility in experimental workflows.

How PubCompare Works

1. Enter protocol details or keywords to search across a large, centralized database of trusted protocols.
2. Use AI-powered protocol comparison to break down protocols into critical steps, identify variables, and generate visual comparative tables.
3. Review reproducibility annotations, protocol shortcut citations, and missing parameter alerts to gauge robustness.
4. Assess related abstracts and citations to identify state-of-the-art methods and relevant publications, including open and closed-access sources.
5. Explore lab products and cross-reference with protocols to ensure compatibility and reproducibility across setups.
6. Save, share, and reuse protocol templates, annotations, and comparisons to support transparent reporting and collaborative research.

Features and Capabilities

• 25+ Million Full Text Protocols from peer-reviewed publications
• 16+ Million Closed Access protocols detected behind paywalls
• 1 Million Full Text protocols from patents
• AI-powered protocol comparator that breaks down protocols into critical steps and key variables
• Enriched protocol annotations and missing parameter detection
• Visual comparative tables to facilitate quick assessment across multiple protocols
• Protocol citation trails and abstraction coverage to identify methods behind paywalls
• Lab products compatibility checks and product-level filtering across protocols
• Scope across multiple domains and study designs to support diverse experimental needs
• User-friendly search and filtering with emphasis on reproducibility and transparency

How It Helps Your Research

• Accelerates literature reviews by quickly locating robust protocols relevant to your experimental model and design
• Enhances reproducibility by highlighting critical steps, parameters, and replicability indicators
• Reduces wasted time and resources by comparing multiple protocols side-by-side and identifying best practices
• Supports collaboration by enabling sharing of annotated protocols and comparisons

Safety and Ethical Considerations

• Use protocols in accordance with institutional guidelines and ensure proper validation and safety assessments before adopting methods.

Core Features

• AI-powered protocol comparator for critical step breakdowns
• Large-scale, multi-source protocol repository (open and closed access)
• Visual protocol comparison tables and reproducibility annotations
• Protocol shortcut citations to access methods behind paywalls
• Product matching to identify compatible lab supplies across protocols
• Reproducibility insights to support robust experimental design
• Open access and patent-derived protocols for broader method coverage